Certain Common Stock of Kowa Co.,Ltd. are subject to a Lock-Up Agreement Ending on 8-MAY-2022. These Common Stock will be under lockup for 180 days starting from 9-NOV-2021 to 8-MAY-2022. Details: In connection with general offering, our shareholders, HIDEICHI CO.,LTD. and Hideaki Tamada, have agreed with Daiwa Securities Co. Ltd. that during the period starting on the date when the issue price is decided and ending on the 180th day from the delivery date of the general offering,without the prior written consent of Daiwa Securities Co. Ltd., they will not sell our shares, securities that can be converted or exchanged for our shares, or securities that represent the right to acquire or receive our shares.