The Board of Directors of the Giant Biogene Holding Co., Ltd. announced that Ms. Yiu Suk Han has tendered her resignation as the joint company secretary of the Company (the "Joint Company Secretary") and the authorised representative all with effect from 28 August 2023. Ms. Yiu has confirmed that she has no disagreement with the Board and there are no matters with regard to her resignation which need to be brought to the attention of the shareholders of the Company or the Stock Exchange. Following the resignation of Ms. Yiu, the Board also announces the appointment of Ms. Yuen Wing Yan, Winnie ("Ms. Yuen"), as the Joint Company Secretary and the authorised representative with effect from 28 August 2023.

Ms. Yuen is currently one of the authorised representatives under Part 16 of the Companies Ordinance (Chapter 622) of the Company and Ms. Yuen meets the requirements under Rules 3.28 and 8.17 of the Listing Rules. After the aforesaid changes, Ms. Yan Yubo ("Ms. Yan") continues to serve as the other Joint Company Secretary. Ms. Yuen is a Director of Corporate Services of Tricor Services Limited, and has over 25 years of experience in the corporate secretarial field.

She has been providing professional corporate services to Hong Kong listed companies as well as multinational, private and offshore companies. Ms. Yuen is currently acting as the company secretary or joint company secretary of a few listed companies on the Stock Exchange. Ms. Yuen is a Chartered Secretary, a Chartered Governance Professional and a Fellow of both The Hong Kong Chartered Governance Institute ("HKCGI") and The Chartered Governance Institute in the United Kingdom.

She is a holder of the Practitioner's Endorsement from HKCGI. The Board would like to express its gratitude to Ms. Yiu for her valuable efforts and contributions to the Company and take the opportunity to express its warmest welcome to Ms.Yuen on her new appointments.