Item 8.01 Other Events

On December 5, 2022, Diffusion Pharmaceuticals Inc. issued a press release announcing the issuance of a letter to its stockholders. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Item 9.01 - Financial Statements and Exhibits



(d) Exhibits

Exhibit                                  Description
Number

99.1       Press Release, issued December 5, 2022

104      Cover Page Interactive Data File (embedded within the Inline XBRL document)



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