ITEM 5.02 DEPARTURE OF DIRECTORS OR CERTAIN OFFICERS; ELECTION OF DIRECTORS; APPOINTMENT OF CERTAIN OFFICERS; COMPENSATORY ARRANGEMENTS OF CERTAIN OFFICERS

On February 23, 2022, the Board of Directors (the "Board") of Centene Corporation (the "Company") approved a request from Michael Neidorff for a paid medical leave of absence from his roles as Chief Executive Officer, Chairman, and a director of the Company (the "Leave of Absence"). The Board also (i) appointed James Dallas as the Acting Chairman of the Board and (ii) appointed an expanded Office of the Chairman, consisting of Sarah London, Vice Chairman of the Board; Brent Layton, the Company's President and Chief Operating Officer; Drew Asher, the Company's Chief Financial Officer; and Shannon Bagley, the Company's Chief Administrative Officer, to oversee the day-to-day management of the Company and discharge the duties of the Chief Executive Officer on an interim basis. Such leadership team will report to James Dallas in his position as Acting Chairman of the Board. The Board continues to be engaged in the previously announced succession process to appoint a new CEO, which is currently targeted for completion no later than Q2 2022.

ITEM 7.01 REGULATION FD DISCLOSURE

A copy of the press release announcing the events described in Item 5.02 above is attached hereto as Exhibit 99.1 and incorporated herein by reference.

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