As previously disclosed, on January 8, 2024, Summit Therapeutics Inc. entered into a lease agreement with Brickell Key Centre, LLC, pursuant to which the Company leased office space for its Miami, Florida headquarter location. The Lease Agreement commenced on February 1, 2024 and has a term of 64 months. The Lease Agreement permitted the Company to sublet any part of the premises with Landlord consent.

On June 27, 2024, the Company entered into two sublease agreements, one with Genius 24C Inc., an affiliate of Robert W. Duggan and one with Duggan Investments Research LLC, an affiliate of Robert W. Duggan. Pursuant to the Genius Sublease Agreement, Genius will sublease from the Company 848 square feet of office space in the Miami HQ for a sixty-two month term for total rental payments of approximately $446,000. Pursuant to the Investments Research Sublease Agreement, Investments Research will sublease from the Company 848 square feet of office space in the Miami HQ for a sixty-two month term for total rental payments of approximately $446,000.