Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Effective December 14, 2022, SmartKem, Inc. (the "Company") appointed Barbra C. Keck as the Company's Chief Financial Officer. In connection with her appointment as Chief Financial Officer, Ms. Keck resigned from the Audit Committee and Compensation Committee but will remain on the board of directors of the Company (the "Board").

Ms. Keck has served as a member of the Board since February 2021. From February 2021 until December 2022, Ms. Keck served as the Chief Financial Officer of Deverra Therapeutics, Inc., a developer of cell therapies. From January 2009 until May 2020, she held positions of increasing responsibility at Delcath Systems, Inc., an interventional oncology company, starting as Controller and ultimately becoming a senior vice president in March 2015 and chief financial officer in February 2017. Ms. Keck received an M.B.A. in Accountancy from Baruch College and a Bachelor of Music in Music Education from the University of Dayton.

Pursuant to the offer letter entered into in connection with her appointment (the "Offer Letter"), Ms. Keck will be entitled to an annual base salary of $300,000 and an annual bonus of up to 40% of her base compensation subject to achievement of key performance indicators as determined by the Board. Ms. Keck will also be eligible for all employee benefits available to full-time employees of the Company.

In connection with her appointment, Ms. Keck was granted options (the "Options") to purchase up to 450,000 shares of the Company's common stock, par value $0.0001 per share (the "Common Stock"), at an exercise price of $2.00 per share under the Company's 2021 Equity Incentive Plan (the "Plan"). Options to acquire 150,000 shares of Common Stock will vest on the first anniversary of Ms. Keck's employment and the remaining Options will vest ratably on a monthly basis thereafter over a two-year period.

The foregoing description of the Offer Letter does not purport to be complete and is qualified in its entirety by reference to the full text of the Offer Letter, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 8-K and incorporated herein by reference.

There is no family relationship between Ms. Keck and any director or executive officer of the Company. There are no transactions between Ms. Keck and the Company that would be required to be reported under Item 404(a) of Regulation S-K.

Item 9.01 Financial Statements and Exhibits

(d) The following exhibits are being filed herewith:



Exhibit    Description
10.1         Offer Letter, effective December 14, 2022, by and between SmartKem,
           Inc. and Barbra Keck.

104        Cover Page Interactive Data File (embedded within the Inline XBRL
           Document).

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