Valuation : Silence Therapeutics plc

Market Cap 59Cr 80Cr 69Cr 65Cr 110.74Cr 7.66TCr 111.75Cr 774.45Cr 298.06Cr 3.89TCr 300.94Cr 294.36Cr 12TCr P/E 2026 *
-25x
P/E 2027 * -20.1x
Enterprise Value 46Cr 62Cr 53Cr 50Cr 86Cr 5.94TCr 87Cr 600.45Cr 231.09Cr 3.01TCr 233.32Cr 228.22Cr 9.57TCr EV / Sales 2026 *
1,424x
EV / Sales 2027 * 557x
Free-Float
69.35%
Yield 2026 *
-
Yield 2027 * -

Last Transcript : Silence Therapeutics plc

Manager TitleAgeSince
Chief Executive Officer 72 01/12/2025
Director of Finance/CFO 54 01/02/2022
Chief Tech/Sci/R&D Officer - 01/01/2021
Director TitleAgeSince
Director/Board Member 63 21/06/2018
Chairman 72 01/01/2004
Director/Board Member 65 05/05/2025
Change 5-day change 1-year change 3-year change Capi.($)
-0.93%-2.73% - - 82Cr
-0.56%-8.08%-3.88%+10.58% 4.64TCr
-2.08%-3.57%+402.72%+533.09% 4.45TCr
+0.12%-5.27%+39.94%+20.50% 4.23TCr
-2.62%-5.76%+8.88%+77.44% 3.99TCr
-1.26%-3.37%+11.87%+40.55% 3.28TCr
+0.16%-3.65% - - 1.71TCr
-0.54%-1.72%+22.34%+115.10% 1.64TCr
-0.03%-3.46%+12.68%+30.90% 1.43TCr
-1.92%-6.94%+78.12%+36.68% 1.33TCr
Average -0.97%-4.30%+71.58%+108.10% 2.97TCr
Weighted average by Cap. -1.09%-4.54%+87.11%+129.36%

Financials

2026 *2027 *
Net sales 3L 4L 4L 4L 6L 4.17Cr 6L 42.15L 16.22L 2.12Cr 16.38L 16.02L 6.72Cr 8L 10.15L 9L 8L 14.03L 9.71Cr 14.16L 98.12L 37.76L 4.92Cr 38.13L 37.29L 16Cr
Net income -4.21Cr -5.7Cr -4.9Cr -4.63Cr -7.88Cr -544.97Cr -7.95Cr -55Cr -21Cr -276.42Cr -21Cr -21Cr -877.99Cr -7.1Cr -9.61Cr -8.26Cr -7.79Cr -13Cr -918.43Cr -13Cr -93Cr -36Cr -465.84Cr -36Cr -35Cr -1.48TCr
Net Debt -13Cr -18Cr -15Cr -15Cr -25Cr -1.72TCr -25Cr -174Cr -67Cr -873.12Cr -68Cr -66Cr -2.77TCr -17Cr -24Cr -20Cr -19Cr -33Cr -2.25TCr -33Cr -227.52Cr -88Cr -1.14TCr -88Cr -86Cr -3.63TCr
Logo Silence Therapeutics plc
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Employees
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