Valuation: Silence Therapeutics plc

Market Cap 62Cr 84Cr 73Cr 69Cr 117.16Cr 8.07TCr 119.1Cr 802.9Cr 313.92Cr 4.04TCr 316.99Cr 310.11Cr 13TCr P/E 2026 *
-12.8x
P/E 2027 * -16.6x
Enterprise Value 49Cr 66Cr 57Cr 54Cr 92Cr 6.35TCr 94Cr 631.42Cr 246.88Cr 3.18TCr 249.29Cr 243.88Cr 11TCr EV / Sales 2026 *
1,487x
EV / Sales 2027 * 116x
Free-Float
69.35%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Silence Therapeutics plc

1 day-1.83%
1 week+14.73%
Current month+30.70%
1 month+40.62%
3 months+92.29%
6 months+173.65%
Current year+125.49%
1 week 13.36
Extreme 13.36
17.58
1 month 9.57
Extreme 9.57
17.58
Current year 4.19
Extreme 4.19
17.58
1 year 4.19
Extreme 4.19
17.58
3 years 1.97
Extreme 1.97
27.72
5 years 1.97
Extreme 1.97
27.72
10 years 1.97
Extreme 1.97
35
Manager TitleAgeSince
Chief Executive Officer 72 01/12/2025
Director of Finance/CFO 54 01/02/2022
Chief Tech/Sci/R&D Officer - 01/01/2021
Director TitleAgeSince
Director/Board Member 63 21/06/2018
Chairman 72 01/01/2004
Director/Board Member 65 05/05/2025
Date Insider Type Main position Quantity % Market Cap.
06/07/26 Sell 8,65,112 0.6105%
02/01/26 Free

Chief Financial Officer

3,75,000 0.2646%
02/01/26 Free

Director

90,000 0.0635%
Change 5-day change 1-year change 3-year change Capi.($)
-1.83%+14.73%+143.52%+124.39% 84Cr
-1.78%-1.68%+1.99%+13.84% 4.92TCr
+0.38%-1.27%+462.30%+575.13% 4.33TCr
-2.61%-0.50%+11.90%+69.76% 4.05TCr
-1.73%-0.56%+25.32%+7.83% 3.98TCr
-0.50%+3.08%+19.91%+47.26% 3.27TCr
+0.27%-3.04% - - 1.62TCr
-0.53%-2.01%+26.19%+117.89% 1.62TCr
+0.49%+0.92%+4.32%+22.16% 1.4TCr
-0.97%+3.84%+78.27%+28.05% 1.34TCr
Average -0.90%+3.85%+85.97%+111.81% 2.66TCr
Weighted average by Cap. -1.06%+2.60%+95.65%+131.88%

Financials

2026 *2027 *
Net sales 3L 4L 4L 4L 6L 4.27Cr 6L 42.46L 16.6L 2.14Cr 16.76L 16.4L 7.1Cr 38.82L 52.59L 45.42L 42.68L 72.98L 50Cr 74.18L 5Cr 1.96Cr 25Cr 1.97Cr 1.93Cr 84Cr
Net income -4.02Cr -5.45Cr -4.71Cr -4.43Cr -7.57Cr -521.43Cr -7.69Cr -52Cr -20Cr -261.12Cr -20Cr -20Cr -867.72Cr -8.31Cr -11Cr -9.72Cr -9.13Cr -16Cr -1.08TCr -16Cr -107.03Cr -42Cr -538.93Cr -42Cr -41Cr -1.79TCr
Net Debt -13Cr -18Cr -16Cr -15Cr -25Cr -1.72TCr -25Cr -171.47Cr -67Cr -863.43Cr -68Cr -66Cr -2.87TCr -17Cr -24Cr -20Cr -19Cr -33Cr -2.25TCr -33Cr -224.23Cr -88Cr -1.13TCr -89Cr -87Cr -3.75TCr
Logo Silence Therapeutics plc
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Employees
88
Date Price Change Volume
14/26/14 $13.71 -1.86% 4,49,934
13/26/13 $13.97 +2.87% 28,14,361
12/26/12 $13.58 -7.74% 54,43,587
11/26/11 $14.72 -4.60% 32,89,354
10/26/10 $15.43 +29.12% 1,62,08,741
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
13.97USD
Average target price
33.00USD
Spread / Average Target
+136.22%

Quarterly revenue - Rate of surprise