Valuation: Silence Therapeutics plc

Market Cap 57Cr 76Cr 67Cr 63Cr 106.99Cr 7.32TCr 107.52Cr 750.79Cr 290.31Cr 3.72TCr 287.25Cr 280.86Cr 12TCr P/E 2026 *
-23.9x
P/E 2027 * -19.2x
Enterprise Value 44Cr 59Cr 51Cr 48Cr 82Cr 5.62TCr 83Cr 576.31Cr 222.84Cr 2.86TCr 220.5Cr 215.59Cr 9.15TCr EV / Sales 2026 *
1,363x
EV / Sales 2027 * 531x
Free-Float
69.35%
Yield 2026 *
-
Yield 2027 * -
1 day+1.60%
1 week-4.58%
Current month-6.13%
1 month-11.50%
3 months+87.87%
6 months+83.79%
Current year+108.88%
1 week 12.1
Extreme 12.1
13.28
1 month 12.1
Extreme 12.1
15.28
Current year 4.19
Extreme 4.19
17.58
1 year 4.19
Extreme 4.19
17.58
3 years 1.97
Extreme 1.97
27.72
5 years 1.97
Extreme 1.97
27.72
10 years 1.97
Extreme 1.97
35
Manager TitleAgeSince
Chief Executive Officer 72 01/12/2025
Director of Finance/CFO 54 01/02/2022
Chief Tech/Sci/R&D Officer - 01/01/2021
Director TitleAgeSince
Director/Board Member 63 21/06/2018
Chairman 72 01/01/2004
Director/Board Member 65 05/05/2025
Date Insider Type Main position Quantity % Market Cap. Importance
06/07/26 Sell 8,65,112 0.6105%
02/01/26 Free

Chief Financial Officer

3,75,000 0.2646%
02/01/26 Free

Director

90,000 0.0635%
Change 5-day change 1-year change 3-year change Capi.($)
+1.60%-4.58%+153.49%+27.64% 76Cr
+1.06%+3.65%+1.25%+29.77% 4.62TCr
+0.23%+4.72%+44.32%+27.27% 4.43TCr
+0.52%-3.15%+349.53%+520.09% 4.22TCr
+1.55%+3.41%+6.40%+76.45% 4.02TCr
+1.75%-0.28%+12.42%+41.11% 2.98TCr
-0.20%+5.49%+23.57%+119.72% 1.72TCr
-3.49%-8.49% - - 1.57TCr
+1.09%+9.93%+24.19%+41.26% 1.53TCr
-2.45%+2.41%-3.16%-35.16% 1.31TCr
Average +0.17%+1.13%+68.00%+94.24% 2.65TCr
Weighted average by Cap. +0.47%+1.71%+73.29%+124.79%

Financials

2026 *2027 *
Net sales 3L 4L 4L 4L 6L 4.12Cr 6L 42.27L 16.34L 2.1Cr 16.17L 15.81L 6.71Cr 8L 10.02L 9L 8L 14.02L 9.6Cr 14.09L 98.39L 38.05L 4.88Cr 37.64L 36.81L 16Cr
Net income -4.21Cr -5.63Cr -4.9Cr -4.64Cr -7.87Cr -538.79Cr -7.91Cr -55Cr -21Cr -273.82Cr -21Cr -21Cr -876.56Cr -7.1Cr -9.48Cr -8.26Cr -7.82Cr -13Cr -908.02Cr -13Cr -93Cr -36Cr -461.46Cr -36Cr -35Cr -1.48TCr
Net Debt -13Cr -18Cr -15Cr -15Cr -25Cr -1.7TCr -25Cr -174.48Cr -67Cr -864.91Cr -67Cr -65Cr -2.77TCr -17Cr -23Cr -20Cr -19Cr -33Cr -2.23TCr -33Cr -228.16Cr -88Cr -1.13TCr -87Cr -85Cr -3.62TCr
Logo Silence Therapeutics plc
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Employees
88
Date Price Change Volume
17/26/17 $12.70 +1.60% 6,90,466
16/26/16 $12.50 +0.32% 9,83,806
15/26/15 $12.46 -4.59% 13,83,436
14/26/14 $13.06 +0.31% 10,95,255
11/26/11 $13.02 -2.18% 6,85,914
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
12.70USD
Average target price
33.00USD
Spread / Average Target
+159.84%

Quarterly revenue - Rate of surprise

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