Valuation: Silence Therapeutics plc

Market Cap 56Cr 75Cr 65Cr 61Cr 104.41Cr 7.2TCr 105.19Cr 733.29Cr 282.12Cr 3.65TCr 281.8Cr 275.55Cr 12TCr P/E 2026 *
-23.4x
P/E 2027 * -18.8x
Enterprise Value 42Cr 57Cr 49Cr 47Cr 79Cr 5.47TCr 80Cr 557.86Cr 214.62Cr 2.78TCr 214.38Cr 209.63Cr 8.85TCr EV / Sales 2026 *
1,313x
EV / Sales 2027 * 509x
Free-Float
69.35%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Silence Therapeutics plc

1 day-4.59%
1 week-8.98%
Current month-7.91%
1 month-9.18%
3 months+78.00%
6 months+80.58%
Current year+104.93%
1 week 12.1
Extreme 12.1
13.81
1 month 12.1
Extreme 12.1
15.28
Current year 4.19
Extreme 4.19
17.58
1 year 4.19
Extreme 4.19
17.58
3 years 1.97
Extreme 1.97
27.72
5 years 1.97
Extreme 1.97
27.72
10 years 1.97
Extreme 1.97
35
Manager TitleAgeSince
Chief Executive Officer 72 01/12/2025
Director of Finance/CFO 54 01/02/2022
Chief Tech/Sci/R&D Officer - 01/01/2021
Director TitleAgeSince
Director/Board Member 63 21/06/2018
Chairman 72 01/01/2004
Director/Board Member 65 05/05/2025
Date Insider Type Main position Quantity % Market Cap. Importance
06/07/26 Sell 8,65,112 0.6105%
02/01/26 Free

Chief Financial Officer

3,75,000 0.2646%
02/01/26 Free

Director

90,000 0.0635%
Change 5-day change 1-year change 3-year change Capi.($)
-4.59%-8.98%+163.42%+25.23% 75Cr
+0.56%-3.38%-1.83%+8.00% 4.58TCr
-0.12%-1.19%+343.42%+545.03% 4.39TCr
+1.51%+4.04%+45.01%+27.38% 4.44TCr
-2.07%-1.42%+4.28%+72.97% 3.94TCr
-0.73%-3.06%+9.63%+38.92% 3.13TCr
-9.49%-11.23% - - 1.57TCr
+4.21%+5.01%+24.99%+121.62% 1.73TCr
+1.83%+3.20%+16.49%+32.73% 1.47TCr
-0.08%-2.81%+79.24%+31.27% 1.3TCr
Average -0.90%-1.98%+76.07%+100.35% 2.66TCr
Weighted average by Cap. -0.27%-1.25%+76.99%+130.17%

Financials

2026 *2027 *
Net sales 3L 4L 4L 4L 6L 4.17Cr 6L 42.5L 16.35L 2.11Cr 16.33L 15.97L 6.74Cr 8L 10.12L 9L 8L 14.09L 9.71Cr 14.19L 98.93L 38.06L 4.92Cr 38.02L 37.18L 16Cr
Net income -4.21Cr -5.68Cr -4.92Cr -4.65Cr -7.91Cr -545.06Cr -7.97Cr -56Cr -21Cr -276.38Cr -21Cr -21Cr -881.41Cr -7.1Cr -9.58Cr -8.29Cr -7.84Cr -13Cr -918.59Cr -13Cr -94Cr -36Cr -465.77Cr -36Cr -35Cr -1.49TCr
Net Debt -13Cr -18Cr -16Cr -15Cr -25Cr -1.72TCr -25Cr -175.43Cr -67Cr -872.98Cr -67Cr -66Cr -2.78TCr -17Cr -23Cr -20Cr -19Cr -33Cr -2.25TCr -33Cr -229.41Cr -88Cr -1.14TCr -88Cr -86Cr -3.64TCr
Logo Silence Therapeutics plc
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Employees
88
Date Price Change Volume
15/26/15 $12.46 -4.59% 13,83,436
14/26/14 $13.06 +0.31% 10,95,255
11/26/11 $13.02 -2.18% 6,85,914
10/26/10 $13.31 -1.77% 6,82,632
09/26/09 $13.55 -1.02% 6,45,880
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
12.46USD
Average target price
33.00USD
Spread / Average Target
+164.85%

Quarterly revenue - Rate of surprise

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