Valuation: Silence Therapeutics plc

Market Cap 58Cr 79Cr 68Cr 63Cr 109.08Cr 7.58TCr 110.53Cr 750.21Cr 292.56Cr 3.81TCr 297.48Cr 291.01Cr 13TCr P/E 2026 *
-19.5x
P/E 2027 * -16.1x
Enterprise Value 45Cr 61Cr 52Cr 49Cr 84Cr 5.84TCr 85Cr 578.43Cr 225.57Cr 2.94TCr 229.36Cr 224.37Cr 9.71TCr EV / Sales 2026 *
1,380x
EV / Sales 2027 * 543x
Free-Float
69.35%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Silence Therapeutics plc

1 day+0.95%
1 week-2.92%
Current month+26.98%
1 month+22.76%
3 months+105.24%
6 months+164.29%
Current year+119.08%
1 week 13.01
Extreme 13.01
14.59
1 month 10.32
Extreme 10.32
17.58
Current year 4.19
Extreme 4.19
17.58
1 year 4.19
Extreme 4.19
17.58
3 years 1.97
Extreme 1.97
27.72
5 years 1.97
Extreme 1.97
27.72
10 years 1.97
Extreme 1.97
35
Manager TitleAgeSince
Chief Executive Officer 72 01/12/2025
Director of Finance/CFO 54 01/02/2022
Chief Tech/Sci/R&D Officer - 01/01/2021
Director TitleAgeSince
Director/Board Member 63 21/06/2018
Chairman 72 01/01/2004
Director/Board Member 65 05/05/2025
Date Insider Type Main position Quantity % Market Cap.
06/07/26 Sell 8,65,112 0.6105%
02/01/26 Free

Chief Financial Officer

3,75,000 0.2646%
02/01/26 Free

Director

90,000 0.0635%
Change 5-day change 1-year change 3-year change Capi.($)
+0.95%-2.92%+143.96%+90.56% 79Cr
+1.09%+5.26%+4.44%+26.03% 5.12TCr
-2.01%+1.69%+467.87%+593.54% 4.54TCr
+2.19%+8.46%+20.04%+92.17% 4.2TCr
+0.86%+8.85%+38.95%+20.17% 4.21TCr
-0.93%-4.80%+17.39%+46.60% 3.19TCr
+0.20%+2.78% - - 1.67TCr
+1.94%+8.17%+38.03%+154.40% 1.71TCr
+0.03%+3.41%+7.12%+35.49% 1.48TCr
+1.14%+5.46%+91.11%+47.00% 1.39TCr
Average +0.55%+2.30%+92.10%+122.88% 2.76TCr
Weighted average by Cap. +0.42%+3.10%+102.75%+148.00%

Financials

2026 *2027 *
Net sales 3L 4L 4L 4L 6L 4.23Cr 6L 41.91L 16.34L 2.13Cr 16.62L 16.26L 7.04Cr 8L 10.23L 9L 8L 14.09L 9.79Cr 14.27L 96.87L 37.78L 4.92Cr 38.41L 37.58L 16Cr
Net income -4.14Cr -5.65Cr -4.84Cr -4.53Cr -7.78Cr -540.54Cr -7.88Cr -53Cr -21Cr -271.54Cr -21Cr -21Cr -898.13Cr -6.63Cr -9.03Cr -7.74Cr -7.24Cr -12Cr -864.38Cr -13Cr -86Cr -33Cr -434.22Cr -34Cr -33Cr -1.44TCr
Net Debt -13Cr -18Cr -16Cr -15Cr -25Cr -1.74TCr -25Cr -171.78Cr -67Cr -871.91Cr -68Cr -67Cr -2.88TCr -17Cr -24Cr -20Cr -19Cr -33Cr -2.27TCr -33Cr -224.63Cr -88Cr -1.14TCr -89Cr -87Cr -3.77TCr
Logo Silence Therapeutics plc
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Employees
88
Date Price Change Volume
22/26/22 $13.33 +1.21% 3,15,575
20/26/20 $13.17 -3.23% 5,85,256
19/26/19 $13.61 -3.48% 9,77,258
18/26/18 $14.10 -1.74% 14,87,596
17/26/17 $14.35 +4.59% 10,02,276
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
13.17USD
Average target price
33.00USD
Spread / Average Target
+150.57%

Quarterly revenue - Rate of surprise