Valuation : Silence Therapeutics plc

Market Cap 66Cr 89Cr 76Cr 72Cr 122.62Cr 8.37TCr 123.54Cr 852.45Cr 330.83Cr 4.28TCr 332.7Cr 325.43Cr 14TCr P/E 2026 *
-21.8x
P/E 2027 * -18.1x
Enterprise Value 52Cr 71Cr 61Cr 57Cr 98Cr 6.67TCr 98Cr 679.51Cr 263.71Cr 3.41TCr 265.21Cr 259.41Cr 11TCr EV / Sales 2026 *
1,610x
EV / Sales 2027 * 642x
Free-Float
69.35%
Yield 2026 *
-
Yield 2027 * -

Last Transcript : Silence Therapeutics plc

1 day+0.31%
1 week+9.16%
Current month+9.16%
1 month+38.30%
3 months+131.87%
6 months+146.99%
Current year+142.93%
1 week 13.09
Extreme 13.0896
15.28
1 month 10.32
Extreme 10.32
17.58
Current year 4.19
Extreme 4.19
17.58
1 year 4.19
Extreme 4.19
17.58
3 years 1.97
Extreme 1.97
27.72
5 years 1.97
Extreme 1.97
27.72
10 years 1.97
Extreme 1.97
35
Manager TitleAgeSince
Chief Executive Officer 72 01/12/2025
Director of Finance/CFO 54 01/02/2022
Chief Tech/Sci/R&D Officer - 01/01/2021
Director TitleAgeSince
Director/Board Member 63 21/06/2018
Chairman 72 01/01/2004
Director/Board Member 65 05/05/2025
Date Insider Type Main position Quantity % Market Cap. Importance
06/07/26 Sell 8,65,112 0.6105%
02/01/26 Free

Chief Financial Officer

3,75,000 0.2646%
02/01/26 Free

Director

90,000 0.0635%
Change 5-day change 1-year change 3-year change Capi.($)
+0.34%+9.16%+209.64%+71.94% 89Cr
+0.97%-0.75%+3.51%+17.79% 4.97TCr
+0.03%-2.73%+430.10%+521.99% 4.5TCr
+2.78%+1.48%+44.43%+20.14% 4.25TCr
+0.89%-3.74%+8.95%+76.61% 4.08TCr
-0.90%-1.74%+15.20%+48.44% 3.29TCr
+2.20%+6.19% - - 1.71TCr
+1.49%-4.51%+24.89%+123.00% 1.63TCr
+1.70%-0.05%+18.53%+28.09% 1.44TCr
+2.69%-1.83%+79.65%+41.80% 1.35TCr
Average +1.17%-1.40%+92.77%+105.53% 2.73TCr
Weighted average by Cap. +1.05%-2.22%+94.58%+128.82%

Financials

2026 *2027 *
Net sales 3L 4L 4L 4L 6L 4.14Cr 6L 42.2L 16.38L 2.12Cr 16.47L 16.11L 6.96Cr 8L 10.14L 9L 8L 14.03L 9.58Cr 14.13L 97.52L 37.85L 4.9Cr 38.06L 37.23L 16Cr
Net income -4.14Cr -5.6Cr -4.83Cr -4.55Cr -7.75Cr -528.8Cr -7.81Cr -54Cr -21Cr -270.36Cr -21Cr -21Cr -888.12Cr -6.63Cr -8.95Cr -7.72Cr -7.27Cr -12Cr -845.61Cr -12Cr -86Cr -33Cr -432.33Cr -34Cr -33Cr -1.42TCr
Net Debt -13Cr -18Cr -16Cr -15Cr -25Cr -1.7TCr -25Cr -172.94Cr -67Cr -868.12Cr -67Cr -66Cr -2.85TCr -17Cr -24Cr -20Cr -19Cr -33Cr -2.22TCr -33Cr -226.15Cr -88Cr -1.14TCr -88Cr -86Cr -3.73TCr
Logo Silence Therapeutics plc
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Employees
88
Date Price Change Volume
03/26/03 $14.78 +0.27% 4,02,002
01/26/01 $14.74 +8.94% 11,34,889
31/26/31 $13.53 +0.82% 4,78,194
28/26/28 $13.42 -0.22% 5,39,704
27/26/27 $13.45 -0.59% 2,83,674
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
14.74USD
Average target price
33.00USD
Spread / Average Target
+123.88%

Quarterly revenue - Rate of surprise