SeqLL Inc. announced a new study demonstrating early cancer detection using SeqLL's single-molecule technology was published in the peer-reviewed journal Nature Biotechnology. The publication's lead authors, Vadim Fedyk and Nir Erez, are graduate students in Dr. Efrat Shema's Laboratory in the Department of Immunology and Regenerative Biology at the Weizmann Institute of Science. The single molecule-based liquid biopsy approach allowed them to assess and decode cell-free nucleosomes, to provide a highly-informative view of histone post-translational modifications, mutant p53, and DNA methylation differences across the cohort of approximately 100 patient samples.

CRC is the third most common cancer worldwide, causing approximately 700,000 deaths every year. PDAC is a devastating disease with a 5-year overall survival of only 11%.