As previously disclosed, on August 16, 2020, Principia Biopharma Inc. entered into an Agreement and Plan of Merger with Sanofi, and Kortex Acquisition Corp. Pursuant to the Merger Agreement, effective immediately after the Effective Time, each of Martin Babler, Alan B. Colowick M.D., M.P.H., Dan Becker, M.D., Ph.D., Simeon George, M.D., Shao-Lee Lin, M.D., Ph.D., Patrick Machado and Shawn Tomasello ceased serving as a member of the board of directors of the Company and each committee thereof and each of Martin Babler, Dolca Thomas, M.D., Christopher Y. Chai, Roy Hardiman and Stefani Wolff ceased serving as an officer of the Company.