OliX Pharmaceuticals Inc. announced that the first patient has been successfully dosed in a Phase 1 clinical trial (NCT05643118), evaluating OLX10212, an investigational RNAi therapeutic intended for the treatment of age-related macular degeneration (AMD), including geographic atrophy (GA) and neovascular (nv) AMD. According to a news release, OLX10212 targets inflammation pathways that play a key role in the development of GA and nvAMD. The Company will evaluate the safety and tolerability of OLX10212 administered by intravitreal injection in up to 60 patients with nvAMD in a Phase 1 clinical trial in a multi-center, single- and multi-dose, dose-escalation study in the US.