Odyssey Health, Inc., f/k/a Odyssey Group International, Inc. announced the formation of Odyssey Neuropharma, Inc., a wholly owned subsidiary, focused on developing drugs to treat neurological disorders. The blood-brain barrier (BBB) represents a significant obstacle for drug delivery to the brain. Many drugs have failed in neuroscience research due to the inability to jump the hurdle that is the BBB.

The Company will utilize its unique intranasal delivery device coupled with its powdered formulations to allow drugs to be delivered more directly to the brain, providing for efficient and quick delivery. This targeted approach requires less drug to accomplish neuroprotection further reducing drug levels in the plasma which minimizes side effects. Odyssey has a portfolio of products planned for development including drugs for mild traumatic brain injury aka concussion, Niemann-Pick type C Disease, and an Organophosphate Nerve Agent antidote.

Odyssey's unique breath propelled intranasal device is lightweight and easy to use. The drug device combination has been developed to increase brain drug exposure in minutes. The olfactory nerve used for the detection of smell provides a direct highway into the brain.

Previous work in humans completed by Odyssey has shown that intranasal administration of spray-dried powders leads to very low plasma concentrations compared to an intravenous route. This finding is highly suggestive that most of the drug of interest is entering the brain and does not go systemic throughout the body. Odyssey's spray-dried powder formulation technology allows for drugs to be designed for ease of delivery with minimal force of breath, painless interaction with the nasal mucosa, targeting to the superior portion of the nasal cavity for direct flow to the brain and particle sizes that can not be inhaled and interrupt lung function.

Odyssey's unique breath-propelled route of administration closes the soft palate and traps the drug of interest in the nasal cavity for longer periods of absorption. Safe, efficient, and targeted approaches for neurological disorders provide a much greater chance of regulatory and patient success.