Odyssey Health, Inc. announced the successful completion of safety measures for the second cohort of their Phase I Multi-Day Ascending Dosing (MAD) clinical trial. Odyssey's trial involves administering PRV-002, the Company's novel drug to treat concussion, to healthy human subjects to determine drug safety. For all cohorts of the trial, the drug was found to be safe and well tolerated.

The Phase I MAD clinical trial consists of a total of 16 healthy subjects. In Cohort I, eight patients received a low dose of drug and in Cohort II, patients received a high dose of drug. In both cohorts the drug was well tolerated and safe with no severe adverse events reported.

Odyssey is currently selecting clinical sites and developing the Investigator's Brochure for the Phase II trial. Concussions represent an ‘unmet' medical need and affect millions worldwide. Repetitive concussions can lead to rapid cognitive decline and emotional lability.

The global market for concussion treatment was valued at $6.9 billion in 2020 and is forecasted to reach $8.9 billion by 2027, according to Grandview Research.