Item 1.01. Entry into a Material Definitive Agreement.

On January 13, 2021, Myomo Inc.'s (the "Company") sublease with Upstatement, LLC, a Massachusetts limited liability company (the "Sublessor"), became effective upon receipt of a third-party consent from Portland North LLC, a Massachusetts limited liability company (the "Landlord"), for approximately 9,094 rentable square feet located on the fourth (4th) and fifth (5th) floors of the building located at 137 Portland Street, Boston, Massachusetts. The term of the Sublease will expire on August 30, 2023, unless earlier terminated in accordance therewith, and the rent under the Sublease shall range from approximately $33,000 per month to $34,000 per month. Rent payments under the Sublease begin June 1, 2021.

The foregoing summary of the terms of the Sublease does not purport to be complete and is qualified in its entirety by reference to the Sublease, a copy of which will be filed as an exhibit to the Company's Annual Report on Form 10-Kfor the fiscal period ending December 31, 2020.

Item 2.03. Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of Registrant.

The information set forth above in Item 1.01 of this Current Report on Form 8-K regarding the Sublease is incorporated into this Item 2.03 by reference.

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