On January 29, 2021, Krystal Biotech, Inc. (the “Company” or “Krystal”) entered into a Purchase and Sale Agreement (the “Agreement”) with Northfield I, LLC, to acquire its second commercial gene therapy facility (“ASTRA”) located in the Pittsburgh, Pennsylvania area for approximately $9.3 million exclusive of $2.4 million in pre-paid rent that will be re-classified as a portion of the purchase price. The 150,000 square foot facility is under construction and is expected to be completed and validated in 2022. The Company exercised its option to buy ASTRA pursuant to the existing lease agreement between the Company and Northfield. The Company currently holds approximately $1.5 million on deposit with Northfield under the existing lease agreement and intends to apply this deposit as a credit against the purchase price at closing.