On February 22, 2022, Stanley Meresman informed Guardant Health, Inc. (the “Company”) that he will not stand for re-election to the Company's Board of Directors (the “Board”) when his current term expires at the Company's next Annual Meeting of Stockholders, which will take place in June 2022. Mr. Meresman informed the Company that his decision was not a result of any dispute or disagreement with the Company, the Company's management or the Board.