Item 2.02. Results of Operations and Financial Conditions.

On January 9, 2023, Guardant Health, Inc. (the "Company") announced certain preliminary unaudited financial information for the quarter and full year ended December 31, 2022. A copy of the press release is being furnished as Exhibit 99.1 to this Current Report on Form 8-K.

Item 7.01. Regulation FD Disclosure.

The Company will post the presentation that it will present at the 2023 J.P. Morgan Healthcare Conference on January 9, 2023 to the Company's website, www.guardanthealth.com, on the "Events & Presentations" page under the "Investors" tab.

The information furnished in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that Section, nor shall it be deemed to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.

Item 9.01. Financial Statements and Exhibits.



(d) Exhibits.

  Exhibit No.         Description
     99.1               Press release by Guardant Health, Inc., dated January 9, 2023
      104             Cover Page Interactive Data File (embedded within the Inline XBRL document)

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