EMvision Medical Devices Limited announced positive safety observations from healthy human trials conducted at the University of Queensland. The purpose of these trials was to test a clinical prototype on healthy human volunteers to provide key learnings and the necessary safety and usability information. EMvision is confident that the information collected from the healthy human trials can be used towards obtaining ethics approval, which is required as a precursor to EMvision undertaking its planned clinical trial later in 2019. This study was undertaken to ISO 14155 guidelines "Clinical investigation of medical devices for human subjects - good clinical practice". Ten volunteers were investigated to assess initial safety and usability of the clinical prototype, including observing acceptable specific absorption rate (SAR) levels and the absence of adverse events. SAR is a measure of the rate of RF (radiofrequency) energy absorption by the body from the source being measured. The calculated SAR values were significantly less than the Institute of Electrical and Electronics Engineers (IEEE) defined exposure limit, indicating the safe use of the presented system. There was a possibility that an effect of the absorbed energy would be an increase in temperature of the tissue. To assess this potential effect, a thermal camera was used to capture the induced temperature on patients while illuminated by microwave signals. Several thermal images of patients were recorded at various stages, i.e., before, during and immediately after the experiment was underway. Results of this sample of ten volunteers indicated that no warming of the tissue was observed, in fact a slight cooling effect was observed due to the coupling liquid within the headset. No adverse events were reported for any volunteer taking part in this study. Usability of the device and the scanning procedure was measured using participant and operator questionnaires collecting observations using a well-established rating scale. The results indicated that participants provided a positive response, with no discomfort and minimal time spent in the device. Configuration of the specific elements within the headset worked well together, including unique antennae materials and construction which allowed excellent signal penetration and rapid data acquisition. Valuable data was acquired to facilitate advancements in the imaging algorithms in the lead up to clinical trials.