Desktop Health ? the trusted production-grade medical 3D printing brand of Desktop Metal, Inc. announced the first patients have been treated with CMFlex, an off-the-shelf 3D printed synthetic bone graft product developed and manufactured by Chicago-based Dimension Inx on the 3D-Bioplotter. CMFlex was co-invented by Dimension Inx co-founders, Dr. Ramille Shah, CSO, Head of R&D, and Dr. Adam Jakus, CTO, Head of Technology Strategy, (pictured left).

The duo have been developing the material and product since 2009 on the Desktop Health 3D-Biop lotter. Founded in 2017, Dimension Inx is a regenerative therapeutics company that designs, develops, and manufactures therapeutic products to restore tissue and organ function. The company owns four Desktop Health 3D-BBioplotter - two used for R&D and two used for manufacturing their commercial CMFlex product.

Dimension Inx received FDA clearance of CMFlex in December of 2022. CMFlex is currently available to a limited number of key surgeons with a broader release to follow later in 2024. The first jaw cases were performed by Dr. Derek Steinbacher, Director of West River Surgery Center (Guilford, CT), Former Professor Plastic surgery and Chief of Oral and Maxillofacial surgery at Yale New Haven Health, and Dr. Brian Farrell, DDS, MD, of the Carolinas Center for Oral & Facial Surgery (Charlotte, NC).

The resulting product is one that surgeons can size for each patient and is uniquely capable of absorbing fluid, which enables it to control bleeding during surgery while assisting the bone remodeling process once implanted. The 3D-Bioplotters is a sophisticated extrusion-based 3D printer that processes liquids, melts, pastes, gels, or other materials, including cells, through a needle tip on a Swiss-made, 3-axis gantry system with high accuracy and repeatability, along with tight controls for temperature, sterility, and design. 3D-BioplotTER offers eight printheads with the widest range of temperatures in bioprinting - from 2degC to 500degC (35.6degF to 932degF) - enabling complex, multi-material medical parts.

3D-Biop lotters is also the world's most cited and researched bioprinter in peer-reviewed scientific and medical journals, with more than 2,490 citations and more than 640 research papers directly produced with the system.