On December 20, 2021, Julie Sunderland, a member of the Board of Directors (the “Board”) of Compass Therapeutics, Inc. (the “Company”), notified the Company of her resignation from the Board and all committees thereof, effective December 31, 2021. Ms. Sunderland’s resignation was not the result of a disagreement with the Company on any matter relating to the Company’s operations, policies or practices. Ms. Sunderland was an early venture investor in the Company and is now moving on to other professional endeavors.