Company Cizzle Biotechnology Holdings Plc

Equities

PSL

GB00BNG2VN02

Biotechnology & Medical Research

Market Closed - London S.E. Other stock markets 10:05:18 06/03/2026 pm IST			5-day change	1st Jan Change
1.550 ^GBX	+10.71%		+14.81%	-

24/02	Cizzle Biotechnology Holdings plc Provides an Update on Progress Towards the Accreditation and Launch of Its Proprietary Test for the Ciz1b Biomarker Test	CI
23/02	Cizzle says process of preparing submission for CLIA near completion	AN

Business description: Cizzle Biotechnology Holdings Plc

Cizzle Biotechnology Holdings Plc is a United Kingdom-based diagnostics development company. The Company is engaged in the development of a blood test for the early detection of lung cancer. Its prototype test is based on the ability to detect a stable plasma biomarker, a variant of CIZ1 known as CIZ1B. CIZ1 is a cell nuclear protein involved in deoxyribonucleic acid (DNA) replication, and the targeted CIZ1B variant is correlated with early-stage lung cancer. Its prototype confirmative test has been developed to address the false positive rates of computed tomography (CT) scanning. The test is intended to address a clear unmet clinical need, which is early detection of lung cancer, when curative surgical resection is possible.

Number of employees: 4

Sales by Activity: Cizzle Biotechnology Holdings Plc

Fiscal Period: December	2020 (GBP)	2021 (GBP)	2022 (GBP)	2023 (GBP)	2024 (GBP)

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Geographical breakdown of sales: Cizzle Biotechnology Holdings Plc

Fiscal Period: December	2020 (GBP)	2021 (GBP)	2022 (GBP)	2023 (GBP)	2024 (GBP)

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Executive Committee: Cizzle Biotechnology Holdings Plc

Manager	Title	Age	Since
Nigel Lee DFI	Director of Finance/CFO	65	14/05/2021
Dawn Coverley CTO	Chief Tech/Sci/R&D Officer	61	02/01/2025

See CIZZLE BIOTECHNOLOGY HOLDINGS PLC governance

Composition of the Board of Directors: Cizzle Biotechnology Holdings Plc

Director	Title	Age	Since
John Treacy BRD	Director/Board Member	44	29/01/2019
Allan Syms CHM	Chairman	69	21/05/2019
Dawn Coverley BRD	Director/Board Member	61	14/05/2021
Nigel Lee BRD	Director/Board Member	65	14/05/2021
Edwin Bower BRD	Director/Board Member	60	25/03/2025

Composition of the Board of Directors

Shareholders: Cizzle Biotechnology Holdings Plc

Name	Equities	%	Valuation
Martin Lang 11.14 %	4,41,63,349	11.14 %	848 378 p
Unicorn Asset Management Ltd. 0.008628 %	34,200	0.008628 %	657 p

List of CIZZLE BIOTECHNOLOGY HOLDINGS PLC shareholders

Company details: Cizzle Biotechnology Holdings Plc

Cizzle Biotechnology Holdings Plc

60 Gracechurch Street

EC3V 0HR, London

+44 20 7469 0930

http://www.cizzlebiotechnology.com

address Cizzle Biotechnology Holdings Plc(PSL)

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CIZZLE BIOTECHNOLOGY HOLDINGS PLC	+10.71%	+14.81%	-6.06%	-63.95%	82.27L
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Weighted average by Cap.	-0.42%	-4.59%	+32.27%	+58.26%