Item 5.07 Submission of Matters to a Vote of Security Holders.

The proposals set forth below were submitted to the stockholders at the Annual Meeting held on June 17, 2021, with each such proposal described in the Proxy Statement.

The number of shares of common stock entitled to vote at the Annual Meeting was 149,330,911. The number of shares of common stock present or represented by valid proxy at the Annual Meeting was 131,658,614. The number of votes cast for and against and the number of abstentions and broker non-votes with respect to each proposal voted upon are set forth below.

Proposal 1 - Election of Directors

The Company's stockholders elected the three (3) director nominees below to the Company's Board of Directors as Class II directors to hold office until the 2024 Annual Meeting of Stockholders of the Company or until their successors are duly elected and qualified.





Director Nominee      Votes For        Votes Withheld
Eric Aguiar, M.D.     112,441,149            8,264,997
Ali Satvat            109,399,398           11,306,748
Jennifer E. Cook      112,740,211            7,965,935

There were 10,952,468 broker non-votes regarding this proposal.

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Proposal 2 - Non-binding Advisory Vote on Compensation of Named Executive Officers.

The Company's stockholders approved,on a non-binding, advisory basis, the compensation of the Company's named executive officers.





 Votes For    Votes Against   Abstentions
104,049,614    12,951,661      3,704,871

There were 10,952,468 broker non-votes regarding this proposal.

Proposal 3 -Non-Binding Advisory Vote on the Frequency of Advisory Votes to Approve the Company's Executive Compensation

With respect to the non-binding advisory vote on the frequency of advisory votes to approve the Company's executive compensation, the option of "one year" received 98.90% of the votes cast and is considered to be the option recommended by the stockholders. The number of votes received for the options of one, two or three years, and the number of abstentions and broker-non-votes, were as follows:





  Votes For       Votes For       Votes For
1 Year Option   2 Year Option   3 Year Option   Abstentions
 115,723,204       801,492         480,332       3,701,118

Proposal 4 - Ratification of Appointment of Independent Registered Accounting Firm

The Company's stockholders ratified the appointment of Deloitte & Touche LLP as the independent registered public accounting firm of the Company for the fiscal year ending December 31, 2021.





 Votes For    Votes Against   Abstentions
131,492,849      144,598        21,167

There were zero broker non-votes regarding this proposal.

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