Arvinas, Inc. announced they will present updated Phase 1/2 data for vepdegestrant (ARV-471) at the 2023 European Society for Medical Oncology (ESMO) Annual Congress. Vepdegestrant is a novel oral PROTAC® estrogen receptor (ER) degrader that is being jointly developed by Arvinas and Pfizer for the treatment of patients with locally advanced or metastatic ER positive/human epidermal growth factor receptor 2 (HER2) negative (ER+/HER2-) breast cancer. This update will be presented during a poster session at the annual congress being held from October 20-24, 2023, in Madrid, Spain.

Poster session details are as follows: Date: Saturday, October 21, 2023. Time: 12:00 ? 1:00 p.m. CEST /6:00 ?

7:00 a.m. EDT. Presentation Number: 390P. Speaker: Erika P. Hamilton, M.D. Vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) estrogen receptor (ER) degrader, in ER+/human epidermal growth factor receptor 2 (HER2)- advanced breast cancer: update of dose escalation results from a phase 1/2 trial.