Aethlon Medical, Inc. Announces Validation Completion for European Patent Protecting Methods of Quantifying Exosomes
January 23, 2018 at 06:45 pm IST
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Aethlon Medical, Inc. announced that validation has completed and the opposition period expired for European Patent Number 2591359, entitled "METHODS AND COMPOSITIONS FOR QUANTIFYING EXOSOMES." The patent was validated in Germany, France, Great Britain, and Spain. In recent years, exosomes have emerged as a significant diagnostic and therapeutic tool for a wide range of disease conditions, including cancer, tuberculosis, Alzheimer's, and chronic traumatic encephalopathy (CTE). This validated European Patent is an important addition to Aethlon Medical's patent portfolio as it protects methods for quantifying any type of exosome captured by lectin affinity using Galanthus nivalis lectin (GNA), Narcissus pseudonarcissus lectin (NPA), Allium sativum lectin (ASA), Lens culinaris lectin (LCH), Sambucus nigra lectin (SNA), Maackia amurensis lectin (MAL) or concanavalin A. The patent has claims encompassing methods of quantifying exosomes associated with CTE, Alzheimer's, cancer, or any other disease condition by contacting a sample having any type of exosome with GNA, NPA, ASA, LCH, SNA, MAL, or conconavalin A immobilized on a substrate, contacting the bound exosomes with a detectable exosome-binding agent, and measuring a signal from the bound detectable exosome-binding agent, thereby quantifying the bound exosomes. This European patent further expands Aethlon Medical's patent position on diagnostic and therapeutic approaches in the field of exosome biology.
Aethlon Medical, Inc. is a medical therapeutic company focused on developing the Hemopurifier, a clinical-stage immunotherapeutic device which is designed to combat cancer and life-threatening viral infections and for use in organ transplantation. The Hemopurifier, in pre-clinical studies, has demonstrated the removal of harmful exosomes from biological fluids, utilizing its lectin-based technology. The Hemopurifier is a United States Food and Drug Administration (FDA) designated Breakthrough Device indicated for the treatment of individuals with advanced or metastatic cancer who are either unresponsive to or intolerant of standard of care therapy, and with cancer types in which exosomes have been shown to participate in the development or severity of the disease. The Hemopurifier also holds an FDA Breakthrough Device designation and an open Investigational Device Exemption application related to the treatment of life-threatening viruses that are not addressed with approved therapies.
AETHLON MEDICAL, INC. 
