Aclaris Therapeutics, Inc. announced effective January 1, 2023, co-founder and current chief executive officer, Dr. Neal Walker, will transition to the role of chair of the board of directors where he will continue to help guide the long-term strategic direction of Aclaris. Dr. Doug Manion will transition from chief operating officer to the role of chief executive officer, while continuing to serve as president. Dr. Manion joined Aclaris as president and chief operating officer in August 2022.

Dr. Manion brings over 25 years of pharmaceutical industry experience in both large and small companies. Prior to joining Aclaris, Dr. Manion served as executive vice president of research and development at Arena Pharmaceuticals until its acquisition by Pfizer Inc. Before joining Arena Pharmaceuticals, Dr. Manion served as chief executive officer of Kleo Pharmaceuticals until its acquisition by BioHaven Pharmaceutical Holding Company Ltd. Between 2005 and 2016, Dr. Manion served in roles of increasing responsibility at Bristol-Myers Squibb, or BMS, most recently as senior vice president, head of specialty development and head of R&D China and Japan. During his tenure at BMS, he held leadership roles overseeing global clinical research, clinical development, pharmacovigilance and biostatistics across various therapeutic areas, including virology, immunology, neurology, cardiology, metabolic diseases, genetically-defined diseases and fibrosis.

Dr. Manion's previous biopharmaceutical experience included leadership roles at GlaxoSmithKline, DuPont Pharmaceuticals and DuPont Merck Pharmaceuticals.