Item 2.05 Costs Associated with Exit or Disposal Activities.

As previously disclosed, on July 25, 2022, Zymergen Inc. (the "Company") announced a reduction in force as part of its efforts to continue to execute on its previously announced strategic plan, including managing costs and conserving cash resources. The initial phase of this reduction in force was implemented on July 26, 2022 and resulted in the termination of approximately 80 employees.

On August 25, 2022, the Company announced a further reduction in force (the "August 2022 Reduction in Force") that is expected to result in the termination of approximately 80 additional employees. The Company estimates it will incur cash-based severance costs of approximately $3.8 million related to the August 2022 Reduction in Force and an aggregate of approximately $7.4 million in cash-based severance costs when combined with the initial reduction in force. The Company also expects to incur stock-based compensation and employee restructuring costs related to these reductions in force, the amount of which has not yet been estimated.

Item 5.02 Departure of Directors or Certain Officers; Election of Directors;


           Appointment of Certain Officers; Compensatory Arrangements of Certain
           Officers.



In connection with the August 2022 Reduction in Force, Zach Serber, the Company's Co-Founder and Chief Science Officer and a member of the Company's board of directors, will be stepping down from his position as Chief Science Officer, effective as of September 22, 2022. Dr. Serber has agreed to continue through such date in order to facilitate a smooth and orderly transition of his responsibilities and is expected to remain on the Company's board of directors following his cessation of employment.

Subject to his timely execution and non-revocation of a release of claims as well as continued compliance with certain restrictive covenants, Dr. Serber will be entitled to (x) a cash lump-sum payment equal to the sum of 12 months of his annual base salary and his full target annual bonus, (y) continued payment of the Company portion of the premiums required for continued healthcare coverage for Dr. Serber and his covered dependents for up to 12 months and (z) full vesting of his unvested equity awards. In the event the Company's acquisition by Ginkgo Bioworks Holdings, Inc. pursuant to that certain Agreement and Plan of Merger, dated July 24, 2022 (as previously announced on the Company's Current Report on Form 8-K dated July 25, 2022), does not occur within one year from the date of such termination, the foregoing severance payments and benefits will be reduced by the Company.

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