On June 4, 2024, Nathan Jorgensen, Ph.D., M.B.A., notified Vor Biopharma Inc. of his resignation as Chief Financial Officer of the Company, effective as of June 21, 2024 (the Effective Date), in order to pursue a new opportunity. Dr. Jorgensen's resignation is not because of a disagreement with the Company on any matter relating to the Company's operations, policies or practices. The Company is currently conducting a search process to identify a new Chief Financial Officer.