Viela Bio announced that N-MOmentum, a pivotal trial of inebilizumab, met its primary and key secondary endpoints in patients with neuromyelitis optica spectrum disorder (NMOSD). The N-MOmentum trial is a randomized, double-masked, placebo-controlled, global registration study that enrolled 231 patients with NMOSD a rare, life-threatening autoimmune disease affecting the central nervous system. The primary analysis demonstrated a 77% reduction in the risk of developing an NMOSD attack in patients treated with inebilizumab monotherapy compared to placebo. Furthermore, secondary analysis demonstrated a reduction in worsening of disability in patients treated with inebilizumab compared to placebo. The safety and tolerability profiles for inebilizumab were acceptable and consistent with previous experience. Additional details from the N-MOmentum trial will be presented at a medical meeting in 2019. NMOSD is a rare, life-threatening autoimmune disease of the central nervous system in which the body’s immune system attacks healthy cells, most commonly in the optic nerves and spinal cord, resulting in severe damage. NMOSD may cause severe muscle weakness and paralysis, loss of vision, respiratory failure, problems with bowel and bladder function and neuropathic pain.1 There is currently no cure or approved treatment for NMOSD.