On July 8, 2022, Moshe Bar-Siman-Tovsubmitted a letter of resignation to the Chairman of the Board of Directors from his position as a Class I director of UpHealth, Inc. On July 11, 2022, the Board accepted Mr. Bar-Siman-Tov'sresignation, which shall be effective as of July 8, 2022. Mr. Bar-Siman-Tov's resignation is not as a result of any disagreements with the Company. Furthermore, on July 11, 2022, the Board appointed Samuel J. Meckey, the Company's new Chief Executive Officer, to serve as a Class I director.

The appointment of Mr. Meckey fills the vacancy created by Mr. Bar-Siman-Tov'sresignation. As a Class I director, Mr. Meckey's term will expire at the Company's annual meeting of stockholders in 2022, or until his successor is duly elected and qualified, or until his earlier resignation, removal or death.