TME Pharma published on Monday an update of the arm evaluating its lead drug candidate, NOX-A12, in combination with radiotherapy and Roche's Avastin in the survival of patients with glioblastoma, a brain cancer.

With a median follow-up to date of 10 months in this arm of the trial, the median overall survival (mOS) has not yet been reached, and five of the six patients (83%) remain alive.

According to TME, the 10-month timeframe is an important benchmark for evaluation, as it is the expected survival for patients with MGMT-unmethylated tumors and incomplete resection.

Data presented in November 2022 had demonstrated a radiographic response of 100% and an mRANO response rate of 83%, which is twice as high as the mRANO response rate reported in comparable studies with bevacizumab and standard of care.

TME Pharma shares were up 2.4% on Monday morning on the Paris Bourse after these announcements, having climbed more than 4% in early trading.

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