Silence Therapeutics plc announced the appointment of J.P. Gabriel as Chief Technical Operations Officer following the retirement of Jørgen Wittendorff, SVP, Technical Operations. In this role, J.P. is responsible for Manufacturing, Process and Analytical Development and Supply Chain. Mr. Gabriel has over 25 years of international pharmaceutical industry experience across multiple therapeutic modalities.

He has held leadership roles in Manufacturing, Quality, Validation and Supply Chain with firms such as Sanofi-Pasteur, Wyeth (now Pfizer) and Genentech/Roche. He most recently served as SVP, Technical Operations at Ocugen, which includes AAV gene therapy, vaccine, and cell therapy development. Before Ocugen, he spent over five years at Ultragenyx where he was responsible for Biologics and mRNA manufacturing for programs spanning clinical and commercial stages of the development lifecycle.

Mr. Gabriel holds an Honors B.Sc. from the University of Guelph in Ontario, Canada and an Advanced Certificate in Regulatory Affairs from the University of San Diego in California.