The Board of Shanghai Bio-heart Biological Technology Co., Ltd. has been informed by Mr. Charles Sheung Wai CHAN ("Mr. Charles Chan") and Mr. Wing Yiu DJEN ("Mr. Djen") that they would resign as independent non-executive Directors in order to devote more time to their other work commitments. Their resignation will take effect from the conclusion of the AGM. Until then, Mr. Charles Chan and Mr. Djen will continue to perform their duties as independent non-executive Directors.

Upon the resignation of Mr. Charles Chan and Mr. Djen, Mr. Charles Chan will also cease to act as the chairman of the Audit Committee and a member of each of the Remuneration Committee and the Nomination Committee, and Mr. Djen will also cease to act as a member of each of the Audit Committee and the Remuneration Committee. Mr. Charles Chan and Mr. Djen have confirmed they have no disagreement with the Board and there are no other matters relating to their resignation that need to be brought to the attention of the shareholders of the Company or the Stock Exchange.