On August 27, 2021, Judith Dunn, Ph.D., a Class III Director on the Board of Directors (the “Board”) of Seelos Therapeutics, Inc., notified the Company of her decision to resign from the Board, effective as of September 1, 2021. Dr. Dunn is resigning due to time constraints relating to her other outside professional and business activities, and there are no disagreements between Dr. Dunn and the Company on any matter related to the Company’s operations, policies or practices.