While SeaSpine Holdings Corporation has seen positive trends in its business, the Company remains mindful of the negative impacts of ongoing and potential future surges in COVID-19 cases on its business, both in the U.S. and abroad. Given the experience of 2020, and due to the uncertain scope and duration of the pandemic, the global resurgence of cases, and uncertain timing of any recovery and economic normalization, the Company cannot reliably estimate the impact of the pandemic on its operations or financial results and, as such, is not issuing financial guidance for 2021 at this time.