Resverlogix Corp. announced preliminary results from the New Zealand based Phase 1 trial with severe kidney (renal) impaired patients. The data showed remarkable results in reducing inflamed protein biomarkers in patients with severe kidney impairment versus healthy control patients. It is believed that this is the first time in medical history that a direct connection of this type can be made between epigenetic regulation and its potential for positive disease impact. Both the healthy group and the severely impaired kidney group received equal amounts of apabetalone. Ongoing expanded analysis of this exploratory data is also planned which will look at Ingenuity Pathway Analysis (IPA). The quick onset of action and improvement of reported CKD risk factors are encouraging for the Company in their planned expansion beyond its current cardiovascular and diabetes program. Detailed data will be submitted for peer reviewed publications. The study explored acute changes in biomarkers relevant to subjects with Stage 4 CKD. Plasma components were analyzed using the SOMAscan® assay, a sensitive, quantitative and reproducible proteomic tool for measuring 1,310 proteins in the human proteome. Eight patients with previously diagnosed Stage 4 CKD not on dialysis (estimated glomerular filtration rate (eGFR) of less than 30 mL/min/1.73m2) were compared to eight matched healthy individuals with normal renal function (eGFR range > 90 mL/min/1.73m2). Protein data was collected following a single oral administration of 100mg of apabetalone before and after multiple time points in both cohorts.