Sosei Group Corporation and PharmEnable Therapeutics announced they have expanded their collaboration to apply their respective technologies to drive novel drug discovery for a second neurological disease target. Sosei Heptares is known for its expertise in receptor protein structure determination, Structure-Based Drug Design (SBDD) and translational development. PharmEnable will apply its proprietary artificial intelligence (AI)-enabled medicinal chemistry platform (chemUNiversE) to design highly specific drug leads for further development.

Expanding their 2021 agreement, the companies will jointly conduct and share the costs of the discovery and the development programme and will co-own any resulting products equally. The companies are already exploiting their complementary capabilities in an ongoing collaboration focused on an initial target receptor, where they have identified promising small molecules with a new binding mode and novel chemotype.