Generex Biotechnology Corporation announced that their COVID-19 vaccine program has reached a milestone with the manufacturing of 33 Ii-Key-SARS-CoV-2 peptides using antigenic epitopes predicted by computational vaccinology algorithms. Provisional patent applications have been filed for these Ii-Key-SARS-2 peptides, protecting intellectual property rights for Generex and COVID-19 vaccine products based on the viral sequences with Ii-Key. Once the peptides pass Quality Assurance testing, they will be shipped to the clinical laboratories conducting the “Ex-Vivo” Human Immune System Screening Program using blood and plasma samples from patients who have recovered from COVID-19 that have already been collected and stored for the screening program. The unique ex-vivo human immune system studies with convalescent blood samples will provide the data to select the best Ii-Key-SARS-CoV-2 peptides for a “Complete Vaccine” that promotes B-Cell production of neutralizing antibodies and activates CD4+ T-Cell responses (TH1) that promote immune memory and potential long-term protection from coronavirus infection. Additionally, the vaccine screening program will address the safety of the Ii-Key-SARS-CoV-2 peptides using a validated in-vitro assay that models the dangerous cytokine storm associated with COVID-19.