Medicenna Therapeutics Corp. Announces Ema Approval of Its Clinical Trial Application to Expand Its Phase 1/2 Ability-1 Study to Europe

Medicenna Therapeutics Corp. announced that the European Medicines Agency ("EMA") has approved the Clinical Trial Application ("CTA") for the conduct of the Phase 1/2 ABILITY-1 (A Beta-only IL-2 ImmunoTherapY) Study with MDNA11 either alone or in combination with pembrolizumab (KEYTRUDA®?) thereby expanding the clinical trial in the European Union ("EU"). MDNA11 is the Company's long-acting, "beta-enhanced not-alpha" IL-2 super-agonist and is currently enrolling patients with advanced solid tumors in the ABILITY-1 trial at clinical trial sites in U.S.A., Canada, Australia, and Korea.

The ABILITY-1 study is designed to assess the safety, pharmacokinetics, pharmacodynamics, and anti-tumor activity of various doses of intravenously administered MDNA11 in patients with advanced, relapsed, or refractory solid tumors and includes an MDNA11 monotherapy arm, as well as a combination arm designed to evaluate MDNA11 in combination with pembrolIZumab (KEYTRU DA®?).