17,283,399 Common Stock of Kala Pharmaceuticals, Inc. are subject to a Lock-Up Agreement Ending on 16-JAN-2018. These Common Stock will be under lockup for 181 days starting from 19-JUL-2017 to 16-JAN-2018. Details: The directors, executive officers and substantially all stockholders have agreed not to offer, pledge, sell, contract to sell, sell any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase, or otherwise transfer or dispose of, directly or indirectly, any shares of our common stock or any securities convertible into or exercisable or exchangeable for common stock without the prior written consent of J.P. Morgan Securities LLC and Merrill Lynch, Pierce, Fenner & Smith Incorporated for a period of 180 days after the date of this prospectus.