Company Gyroscope Therapeutics Holdings plc

Gyroscope Therapeutics Holdings plc, formerly Gyroscope Therapeutics Holdings Limited, is a clinical-stage gene therapy company. The Company develop gene therapy beyond rare diseases. It offers therapies to treat diseases of the eye that cause vision loss and blindness. The Company's investigational gene therapy, GT005, is in Phase II clinical trials for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration (AMD), a cause of blindness. The Company develops a pipeline of recombinant adeno-associated virus (rAAV), vector-based gene therapy candidates targeting genetic variants in the pathway to be key drivers of AMD. Its gene therapies are designed as one-time treatments. The Company's lead programs, GT005 and GT011, focus on two key targets such as Complement Factor I (CFI) and factor H like-1 (FHL1), a variant of Complement Factor H (CFH). Its gene therapy, GT005, is designed to restore balance to a system by production of CFI, a regulatory protein.

Number of employees: 179