Brickell Biotech, Inc. (the ‘Company') announced that Jose Breton, the Company's Controller and Chief Accounting Officer, and its principal accounting officer, has notified the Company that he will be resigning from the Company effective on June 15, 2022, to pursue another opportunity. Mr. Breton's departure is not the result of any disagreement with the Company on any financial disclosures, accounting matters or any matter relating to the Company's operations, policies or practices. Albert N. Marchio, II, the Company's Chief Financial Officer, will become the Company's principal accounting officer, in addition to the Company's principal financial officer, on June 15, 2022.

Mr. Marchio, age 69, has been the Company's Chief Financial Officer since December 2020. He has been with Danforth Advisors since May 2019, providing financial consulting services on a project/interim basis for various public and private life sciences companies. Previously, Mr. Marchio served in various finance and accounting roles at Edge Therapeutics, Inc. (now known as PDS Biotechnology Corporation), a clinical-stage biopharmaceutical company, including Chief Accounting and Administrative Officer from October 2016 to November 2018, Interim Chief Financial Officer from March 2017 to October 2017, Chief Accounting and Operations Officer from March 2014 to October 2016, and Chief Financial Officer from December 2011 through March 2014.

Mr. Marchio was a Managing Operating Partner with Three Fields Capital, a multi-strategy healthcare-focused investment firm, and provided consulting services to life science companies through Rockabye Valley Consulting from January 2009 to May 2013. Previously, Mr. Marchio served as the Executive Vice President, Chief Financial Officer of Informed Medical Communications from February 2008 to October 2009, and as the Vice President, Treasurer of MedPointe Pharmaceuticals from 2006 to January 2008. He began his career in life sciences as the Vice President, Treasurer of Alpharma, Inc. from 1992 to 2005.

Mr. Marchio holds a B.A. in Economics from Muhlenberg College, an M.B.A. in Professional Accounting from Rutgers Graduate School of Business, and a Post-M.B.A. Certificate in Taxation from Bernard Baruch College of the City University of New York.