Freeline Therapeutics Holdings plc announced leadership transformation with the appointment of Michael J. Parini as Executive Director. Mr. Parini assumed the role of Executive Director effective immediately, replacing former CEO Theresa Heggie. Since March of 2021, Mr. Parini served as the Company’s President and Chief Operating Officer (“COO”) and is an experienced public company biotechnology executive with previous leadership roles at both Vertex Pharmaceuticals Inc. and Pfizer Inc. The company announced that Alison Long, MD, PhD, SVP, Head of Clinical Development, will serve in the role of interim Chief Medical Officer (“CMO”) while an external search for a new CMO is conducted. Dr. Long has been instrumental in catalyzing the momentum in the Company’s clinical and pre-clinical programs. She is an established leader with 30 years of combined clinical and industry experience, including extensive gene therapy drug development experience previously leading clinical departments and programs at uniQure N.V. and, most recently, Spark Therapeutics Inc., where she was Head of Clinical Research & Development.