Evelo Biosciences, Inc. on January 31, 2023, Stephen J. Carriere, the Company's Chief Accounting Officer, was informed that his position was being eliminated in connection with the Workforce Reduction. On the same date, the Board appointed Marella Thorell, the Company's Chief Financial Officer, Senior Vice President, Treasurer and principal financial officer, as the Company's principal accounting officer effective upon Mr. Carriere's departure. Mr. Carriere is expected to serve in his position through March 31, 2023.