Knight Therapeutics Inc. and Ember Therapeutics, Inc. announced an expansion of their exclusive distribution agreement signed in August 2015. Pursuant to the amendment, Knight's territorial rights to Ember's Bone Morphogenetic Protein-7 (BMP-7) pipeline, which originally included Canada, Israel, Russia and sub-Saharan Africa, have been expanded to include Romania and the Caribbean. Additionally, Knight has acquired the exclusive distribution rights for two diversified products recently acquired by Ember: Migralex, a commercially-available over-the-counter medication for treating pain, and ICX-RHY/Vavelta, a development stage regenerative medicine asset, in all of the above-mentioned territories.