Changmao Biochemical Engineering Company Limited announced that Mr. Zhou Zhi Wei proposed to resign as the independent supervisor of the Company with effect from 18 June 2022 as he would offer himself for election as independent non-executive Director in the forthcoming annual general meeting of the Company. Mr. Zhou Zhi Wei has confirmed that he has no disagreement with the Board in any respect and, there is no other matter in relation to his resignation that needs to be brought to the attention of the shareholders of the Company (the "Shareholders") or the Stock Exchange. The Board hereby announced that, Prof. Ouyang Ping Kai, Ms. Wei Xin and Ms. Au Fung Lan, proposed to resign as independent non-executive Directors and from their respective positions in the committee under the Board with effect from 18 June 2022, as each of them has served as an independent non-executive Director for more than 9 years.

Each of Prof. Ouyang Ping Kai, Ms. Wei Xin and Ms. Au Fung Lan has confirmed that he/she has no disagreement with the Board in any respect and, there is no other matter in relation to his/her resignation that needs to be brought to the attention of the Shareholders or the Stock Exchange.