CARDIO DIAGNOSTICS HOLDINGS, INC. Cardio Diagnostics Holdings, Inc. announces that the U.S. Patent and Trademark Office has issued a notice of allowance to University of Iowa Research Foundation ("UIRF") for U.S. Application No. 17,857,723 titled Compositions and Methods for Detecting Predisposition to Cardiovascular Disease, which is exclusively licensed to the Company from UIRF, and that was co-invented by Cardio Diagnostics' founders, Meesha Dogan, Ph.D., and Robert Philibert, MD Ph.D., the Chief Executive Officer and Chief Medical Officer of the Company, respectively. This is the second U.S. patent being issued in this patent family.
Patents in this patent family have also been issued in the European Union, China, India, and Australia. Among Escalating CVD Burden, Company Continues to Expand IP Portfolio: According to the American Heart Association, cardiovascular disease (CVD) claims 2,552 lives daily in the United States, translating to a death every 34 seconds. Heart disease, which includes heart attacks, has been the leading cause of death in the United States for 100 years.
On average, a heart attack occurs every 40 seconds in the U.S., with around 605,000 new and 200,000 recurrent heart attacks reported annually. Unfortunately, an estimated 170,000 of these heart attacks are silent, occurring without significant symptoms. This can mean that many Americans with a silent event are not being identified as at high risk early enough, nor are they being identified after the event. These figures underscore the critical health burden posed by CVD and heart disease in the U.S., highlighting the urgent need for enhanced prevention, detection, management, and treatment strategies.
The Company continues to expand the IP portfolio protections associated with its Integrated Epigenetic-Genetic Engine technology, which lies at the heart of its solutions to this growing burden. The Company's IP portfolio also encompasses its clinical blood tests, Epi+Gen CHDTM and PrecisionCHDTM, and software solutions, HeartRiskTM and CardioInnovate360TM. Solutions Built on Current IP Portfolio: Epi+Gen CHD: An integrated genetic-epigenetic blood test to assess the three-year risk for coronary heart disease (CHD) events, particularly heart attacks or sudden death associated with CHD.
PrecisionCHD: An integrated genetic-epigenetic blood test to aid in diagnosing coronary heart disease. HeartRisk: A cardiovascular disease risk intelligence platform to enable data-driven multi-stakeholder collaborations among patients, innovative providers, health plans, employers, and governmental entities to drive transformative risk stratification in heart disease and enhance earlier prevention and interventions. CardioInnovate360: A biopharma research solution that offers three pivotal capabilities: the identification of novel biomarkers and pathways critical in CVD pathogenesis, patient stratification for enhanced clinical trial efficacy, and the development of non-invasive, scalable post-market surveillance and companion diagnostic tests.
The Company's AI-driven integrated epigenetic-genetic technologies for cardiovascular disease are scalable, accessible, and highly sensitive. The Company's IP strategy is designed to enhance the global protections of its one-of-a-kind technology.
