Proxy

Statement

Notice of Annual Meeting of Shareholders

23

Table of contents

LETTER TO CARDINAL HEALTH SHAREHOLDERS

2

NOTICE

4

PROXY SUMMARY

5

About Us

5

Fiscal 2023 Performance

5

Our 2023 Board Nominees

7

Governance and Board Highlights

8

Shareholder Engagement

8

Agreement with Elliott

8

Approach to ESG Topics

10

Virtual Annual Meeting

11

Roadmap to Voting Matters

11

How to Vote in Advance of the Annual Meeting

11

ForwardLooking Statements

12

CORPORATE GOVERNANCE

13

PROPOSAL 1 - Election of Directors

13

Board Membership Criteria: What We Look For

13

Our Director Nominees

14

Our Board's Composition and Structure

21

Our Board's Primary Role and Responsibilities and Processes

26

Shareholder Engagement

32

Standards of Business Conduct

33

Related Person Transactions Policy and Process

33

Director Compensation

34

AUDIT COMMITTEE MATTERS

36

PROPOSAL 2 - Ratification of Appointment of Ernst & Young LLP as Independent Auditor

36

Audit Committee Report

36

Fees Paid to Ernst & Young LLP

37

Policy on PreApproval of Services Provided by Ernst & Young LLP

37

EXECUTIVE COMPENSATION

38

PROPOSAL 3 - Advisory Vote to Approve the Compensation of Our Named Executive Officers

39

PROPOSAL 4 - Advisory Vote on the Frequency of Future Advisory Votes to Approve the Compensation of

Our Named Executive Officers

39

Compensation Discussion and Analysis

40

Human Resources and Compensation Committee Report

54

Executive Compensation Tables

55

Pay Ratio Disclosure

67

Pay Versus Performance

68

Equity Compensation Plan Information

71

SHAREHOLDER PROPOSALS

72

Proposal 5 - Executives to Retain Significant Stock

72

Proposal 6 - Shareholder Ratification of Excessive Termination Pay

74

SHARE OWNERSHIP INFORMATION

76

Beneficial Ownership

76

Delinquent Section 16(a) Reports

77

OTHER MATTERS

78

General Information About the Annual Meeting

78

Communicating with the Board

80

Shareholder Recommendations for Director Nominees

80

Submitting Proxy Proposals and Director Nominations for the Next Annual Meeting of Shareholders

81

Corporate Governance Documents

81

Transfer Agent

81

ANNEX A: USE OF NONGAAP FINANCIAL MEASURES

82

Exclusions from NonGAAP Financial Measures

82

Fiscal 2023 GAAP to NonGAAP Reconciliations

83

Definitions

83

1

2

GREGORY B. KENNY

Chairman of the Board

CARDINALHEALTH 2023 Proxy Statement

LETTER TO CARDINAL HEALTH SHAREHOLDERS

SEPTEMBER 27, 2023

The past year brought about key changes at Cardinal Health and, with them, strong results. The Board and management remain committed to our refreshed strategic priorities, and we look forward to continuing this work in the year ahead.

FISCAL 2023 PERFORMANCE

We delivered strong financial performance in fiscal 2023, growing revenue and earnings at the enterprise level. We grew Pharmaceutical segment profit an impressive 13%, and, in the Medical segment, we drove significant sequential improvement in operating performance - from a segment loss in the first quarter to over $80 million of segment profit in the fourth quarter. We also generated $2.8 billion of operating cash flow and returned $2.5 billion to shareholders through share repurchases and dividends.

TAKING ACTION TO MAXIMIZE AND SUSTAIN VALUE

As a result of the Board's succession planning process, in August 2022, we named Jason Hollar as the company's new CEO. Under Jason's leadership, we took decisive action this year to advance our three strategic priorities: building on the growth and resiliency of our Pharmaceutical segment; executing our Medical Improvement Plan initiatives; and relentlessly focusing on shareholder value creation. Consistent with what we shared at our Investor Day in June, our strong fiscal 2023 results were achieved through a commitment to prioritize the core of our business and to better serve our customers, so they, in turn, could focus on caring for their patients.

We simplified our operations by streamlining our organizational structure, exiting noncore product lines, and rationalizing our geographic and manufacturing footprints to meet our current business needs. We made key leadership changes, adding talent in critical positions across the enterprise. We formed and recently extended the term of the Board's Business Review Committee tasked with evaluating our strategy, portfolio, capital allocation framework, and operations. Key outputs of this review to date include the completion of a review of the Pharmaceutical segment and the launch of our new NavistaTM Network supporting community oncologists, our recent announcement of further investment in our Nuclear and Precision Health Solutions business, and the merger of the segment's OutcomesTM business into Transaction Data System.

UPDATES TO THE COMPOSITION OF OUR BOARD

The cooperation agreement we entered into with Elliott Management last September included the addition of four new independent directors, each of whom bring a depth of experience and skills, including healthcare and technology, which are core to our strategic direction. These new directors were welcomed by our existing directors, and they contributed to the Board's dialogue over the past year.

As noted in the proxy statement, Carrie Cox and Bruce Downey will be departing the Board when their terms expire this year. Both Carrie and Bruce have provided indispensable guidance over the past 14 years, helping to position Cardinal Health well for the future. On behalf of the Board, I would like to thank Carrie and Bruce for their many years of service and valuable contributions.

Following Carrie's and Bruce's departures, the total number of directors will be reduced to eleven, ten of whom are independent and seven of whom are gender or racially or ethnically diverse.

OPERATING SUSTAINABLY

The Board is highly engaged on our environmental, social, and governance, or ESG, priorities and provides oversight of the company's overall efforts through our Governance and Sustainability Committee. As detailed in our robust ESG report released this past January, we remain steadfast in our strategic approach to deliver a sustainable future. We believe that our existing ESG initiatives align well with, and can help drive, our existing business strategies. Our ESG priorities are organized into four broad categories focused on empowering our people, creating value for our customers and communities, operating sustainably and responsibly, and having strong governance, ethics, and compliance. These priorities inform our ESG strategies, goals, and disclosure. Details on progress against key goals are available in our ESG reports and on our website.

SHAREHOLDER ENGAGEMENT

This past summer, the company contacted shareholders representing 52% of our outstanding shares and met with shareholders representing 37% of our outstanding shares. Another independent director and I participated in select meetings with shareholders. In these discussions, we provided updates on our strategy and ongoing business review process, Board composition and refreshment, senior leadership transitions, executive compensation, and sustainability topics. These are important conversations, and we greatly value the insights that our shareholders provide.

LOOKING FORWARD

Our success would not be possible without the commitment of our employees, who remain focused on our mission to improve the lives of people every day. They continue to deliver for our customers and are foundational to our success.

On behalf of our Board, I thank you for your share ownership and continued support of Cardinal Health. Following a strong first year under Jason Hollar's leadership, the Board is excited to oversee execution of the company's strategic priorities designed to achieve our targeted growth for fiscal 2024 and beyond. We look forward to working with you and all our partners to ensure that Cardinal Health continues its essential role in healthcare.

Sincerely,

Gregory B. Kenny

Chairman of the Board

CARDINALHEALTH 2023 Proxy Statement

3

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Cardinal Health Inc. published this content on 25 September 2023 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 27 September 2023 16:37:45 UTC.