Certain Common Stock of Avenue Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 4-JAN-2023. These Common Stock will be under lockup for 90 days starting from 6-OCT-2022 to 4-JAN-2023.

Details:
The company,all of the directors, officers and the holders of 10% of the outstanding shares of Common Stock have agreed with the underwriters, subject to certain exceptions, not to sell, transfer or dispose of, directly or indirectly, any of the Common Stock or securities convertible into or exercisable or exchangeable for the Common Stock for a period of 90 days after the date of the final closing of this offering.