ATyr Pharma, Inc. Reports Earnings Results for the Fourth Quarter and Full Year Ended December 31, 2022
March 10, 2023 at 02:34 am IST
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aTyr Pharma, Inc. reported earnings results for the fourth quarter and full year ended December 31, 2022. For the fourth quarter, the company reported revenue was USD 10.39 million. Net loss was USD 7.52 million compared to USD 8.56 million a year ago. Basic loss per share from continuing operations was USD 0.26 compared to USD 0.31 a year ago.
For the full year, revenue was USD 10.39 million. Net loss was USD 45.34 million compared to USD 33.77 million a year ago. Basic loss per share from continuing operations was USD 1.6 compared to USD 1.77 a year ago.
aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs. Efzofitimod is a tRNA synthetase derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS). ATYR0101 binds directly to latent-transforming growth factor beta-binding protein 1 (LTBP1), which regulates transforming growth factor beta (TGFb). Its ATYR0750 is a fusion protein derived from a domain of alanyl-tRNA synthetase (AARS).