On March 25, 2024, Susan L. Drexler, Interim Chief Financial Officer, principal financial officer and principal accounting officer of Aileron Therapeutics, Inc. notified the Company of her resignation, effective as of March 25, 2024. Ms. Drexler has agreed to continue to provide consulting and advisory services to the Company under the terms of the Company?s consulting agreement with Danforth Advisors, LLC. To replace Ms. Drexler, the Board of Directors of the Company appointed Charles Garner to serve as the Company?s principal financial officer and principal accounting officer, effective as of March 25, 2024.

Separately, the Company and Mr. Garner have agreed that his employment with the Company will end effective as of May 15, 2024 (the ?Separation Date?). In connection with this agreement, the Company entered into a letter agreement with Mr. Garner confirming that, unless Mr. Garner terminates his employment without good reason or the Company terminates his employment for cause, in each case prior to the Separation Date, Mr. Garner will be entitled to receive twelve (12) months? base salary in the form of severance payments, less statutory deductions and withholdings, payable in the form of salary continuation and payment for any accrued unused paid time off.

Mr. Garner, age 48, has served as the Company?s Senior Vice President, Finance, since October 2023. Prior to becoming Senior Vice President, Finance, Mr. Garner was Chief Financial Officer of Lung Therapeutics, Inc., or Lung, from December 2018 to October 2023, when it was acquired by the Company, and served as Secretary and Treasurer of Lung from February 2020 to October 2023. Prior to joining Lung, Mr. Garner was a finance consultant providing strategic and financial advisory services to Lung and other biopharmaceutical companies from October 2015 to December 2018.

From October 2013 to October 2015, Mr. Garner served as the Chief Financial Officer, Chief Business Officer and Treasurer for Recro Pharma, Inc., a specialty pharmaceutical company. From March 2010 to May 2011, Mr. Garner served as a Director in the Merchant Banking Group of Burrill & Company, a financial services firm focused on the life sciences industry. From 2008 to May 2010, Mr. Garner was self-employed providing consulting and financial advisory services.

From 1999 to 2008, Mr. Garner worked in the Healthcare Investment Banking Group of Deutsche Bank Securities. Mr. Garner began his career at PricewaterhouseCoopers, in its Business Assurance Group. Mr. Garner received his Bachelors of Business Administration, high distinction, with a concentration in accounting and finance from the University of Michigan.